Article
Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities.
Biochemical and biophysical research communications - 21 Jun 2013
Yao Ye, Chen Linjun, Wei Wei, Deng Xiaohui, Ma Liyuan, Hao Siguo
Abstract excerpt
Tumor cell-derived exosomes (TEX) have been widely used to induce antitumor immune responses in animal models and clinical trials. However, the efficiency of the antitumor immunity that is induced by TEX is still relatively weak. In this study, we compared the antitumor immunities between EG7 tumor cell-derived exosomes (EXO(EG7)) and EXO(EG7)-targeted dendritic cells (DC(EXO)). We found that EXO(EG7) harbored...
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