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Article

Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity.

BMC cardiovascular disorders - 26 May 2016

Sente Tahnee, Van Berendoncks An M, Jonckheere An I, Rodenburg Richard J, Lauwers Patrick, Van Hoof Viviane, Wouters An, Lardon Filip, Hoymans Vicky Y, Vrints Christiaan J

Abstract excerpt

BACKGROUND: Peripheral skeletal muscle wasting is a common finding with adverse effects in chronic heart failure (HF). Whereas its clinical relevance is beyond doubt, the underlying pathophysiological mechanisms are not yet fully elucidated. We aimed to introduce and characterize the primary culture of skeletal muscle cells from individual HF patients as a supportive model to study this muscle loss. METHODS AND...

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Identifiers

PMID: 27228977
DOI: 10.1186/s12872-016-0278-3
PMCID: PMC4880810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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