Article

The transcriptomic signature of age and sex is not conserved in human primary myocytes

2024-12-18

Abstract excerpt

<h4>Background</h4> Human primary muscle cell (HPMC) lines derived from skeletal muscle biopsies are potentially powerful tools to interrogate the molecular pathways underlying fundamental muscle mechanisms. HPMCs retain their genome in culture, but many endogenous circulating factors are not present in the in vitro environment, or at concentrations that do not mirror physiological levels. To address the assumpt...

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Literature Corpus work: bd857a2f-a225-5e4e-a23a-c5cd3cac90d0
DOI: 10.1101/2024.12.17.629041

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