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Article

Reductions in Gray Matter Linked to Epigenetic HIV-Associated Accelerated Aging

18 Feb 2021

Abstract excerpt

A growing literature suggests a relationship between HIV-infection and a molecular profile of age acceleration. However, despite the widely known high prevalence of HIV-related brain atrophy and HIV-associated neurocognitive disorder (HAND), epigenetic age acceleration has not been linked to HIV-related changes in structural MRI. We applied morphological MRI methods to study the brain structure of 110 virally...

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PMID: 33822880
DOI: 10.1093/cercor/bhab045

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