Interleukin-6 and rs1800796 locus single nucleotide polymorphisms in response to hypoxia/reoxygenation in hepatocytes.

doi:10.3892/ijmm.2016.2595

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Article

Interleukin-6 and rs1800796 locus single nucleotide polymorphisms in response to hypoxia/reoxygenation in hepatocytes.

International journal of molecular medicine - 1 Jul 2016

Wang Zhaowen, Wu Shaohan, Liao Jianhua, Zhong Lin, Xing Tonghai, Fan Junwei, Peng Zhihai

Abstract excerpt

Ischemia-reperfusion injury due to hypoxia/reoxygenation (H/R) is one of the main causes of liver damage during liver surgery. Donor interleukin-6 (IL-6) rs1800796 single nucleotide polymorphisms (SNPs) affect the metabolism of tacrolimus following liver transplantation-related hepatic H/R. This study investigated the response of IL-6 and its promoter polymorphisms to hepatic H/R in liver parenchymal cells. The...

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PMID: 27221654
DOI: 10.3892/ijmm.2016.2595
PMCID: PMC4899033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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