Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ginsenoside metabolite compound K exerts its anti-inflammatory activity by downregulating memory B cell in adjuvant-induced arthritis.

Pharmaceutical biology - 1 Jul 2016

Chen Jingyu, Wang Qingtong, Wu Huaxun, Liu Kangkang, Wu Yujing, Chang Yan, Wei Wei

Abstract excerpt

CONTEXT: Compound K (CK, 20-O-d-glucopyranosyl-20(S)-protopanaxadiol), a novel ginsenoside metabolite, is structurally a member of the dammarane-type triterpene saponins. Several studies have identified the anti-inflammatory activity of CK. Our previous study demonstrated that CK exerted its anti-inflammatory effect via inhibition of abnormal activation and differentiation of T cells. However, its mechanism of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents
Share to Arthritis, Experimental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD40 Antigens

Share to CD40 Ligand

Share to Immunologic Memory

Share to Joints

Share to Rats, Sprague-Dawley

Share to Spleen

Source

Identifiers

PMID: 27218142
DOI: 10.3109/13880209.2015.1074254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The ginsenoside metabolite compound K exerts its anti-inflammatory activity by downregulating memory B cell in adjuvant-induced arthritis.PMID 27218142Read ↗

Novel disease-modifying anti-rheumatic drug iguratimod suppresses chronic experimental autoimmune encephalomyelitis by down-regulating activation of macrophages/microglia through an NF-κB pathway.Semantic proximity Read ↗

Targeted Modulation of Inflammatory Lymphocytes and Neurogenesis/Neuroprotection Associated Genes by Curcumin and a Novel Derivative of Curcumin on Mice Experimental Autoimmune Encephalomyelitis ModelSemantic proximity Read ↗

Macrophage Polarization Towards M2 Phenotype by Curcuminoids Through NF-κB Pathway Inhibition in Adjuvant-Induced Arthritis.Semantic proximity Read ↗

Aristolochic acid IVa ameliorates arthritis in SKG Mice by regulating macrophage polarization and Th17/Treg balanceSemantic proximity Read ↗

An herbal formula attenuates collagen-induced arthritis via inhibition of JAK2-STAT3 signaling and regulation of Th17 cells in mice.Semantic proximity Read ↗

Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19+CD24hiCD27+ Breg Cells.Semantic proximity Read ↗

CD20 <sup>+</sup> T cells are associated with inflammatory responses in experimental arthritisSemantic proximity Read ↗

Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.