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Article

An herbal formula attenuates collagen-induced arthritis via inhibition of JAK2-STAT3 signaling and regulation of Th17 cells in mice.

Oncotarget - 4 Jul 2017

Wu Xin, Shou Qiyang, Chen Cuiwei, Cai Hao, Zhang Jida, Tang Songqi, Cai Baochang, Tang Dongxin, Cao Gang

Abstract excerpt

Wenjinghuoluo prescription, a traditional Chinese medicine compound treatment of rheumatoid arthritis characterized by wind-cold-dampness arthralgia, contains five herbs, namely, C. cassia Presl., Cinnamomum cassia Presl., Paeonia lactiflora Pall., Saposhnikovia divaricate (Turcz.) Schischk., and Clematis chinensis Osbeck. We have reported that WJHL could inhibit the production of inflammatory mediators in immune...

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Source

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Identifiers

PMID: 28562338
DOI: 10.18632/oncotarget.17797
PMCID: PMC5546477

Genes

JAK2
STAT3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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