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Article

Mood, stress and longevity: convergence on ANK3.

Molecular psychiatry - 1 Aug 2016

Rangaraju S, Levey D F, Nho K, Jain N, Andrews K D, Le-Niculescu H, Salomon D R, Saykin A J, Petrascheck M, Niculescu A B

Abstract excerpt

Antidepressants have been shown to improve longevity in C. elegans. It is plausible that orthologs of genes involved in mood regulation and stress response are involved in such an effect. We sought to understand the underlying biology. First, we analyzed the transcriptome from worms treated with the antidepressant mianserin, previously identified in a large-scale unbiased drug screen as promoting increased...

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Source

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Identifiers

PMID: 27217151
DOI: 10.1038/mp.2016.65
PMCID: PMC9798616

Genes

ANK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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