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Article

Involvement of 3D osteoblast migration and bone apatite during in vitro early osteocytogenesis.

Bone - 1 Jul 2016

Robin Marc, Almeida Claudia, Azaïs Thierry, Haye Bernard, Illoul Corinne, Lesieur Julie, Giraud-Guille Marie-Madeleine, Nassif Nadine, Hélary Christophe

Abstract excerpt

The transition from osteoblast to osteocyte is described to occur through passive entrapment mechanism (self-buried, or embedded by neighboring cells). Here, we provide evidence of a new pathway where osteoblasts are "more" active than generally assumed. We demonstrate that osteoblasts possess the ability to migrate and differentiate into early osteocytes inside dense collagen matrices. This step involves MMP-13...

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Source

Identifiers

PMID: 27150828
DOI: 10.1016/j.bone.2016.04.031

Genes

DMP1
IBSP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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