Article
Mutation Analysis of PRKAR1A Gene in a Patient with Atrial Myxoma.
Clinical laboratory - 1 Jan 2016
Massobrio Laura, Nasti Sabina, Martinuzzi Claudia, Chiarella Francesco, Montecucco Fabrizio, Rosa Gian Marco, Valbusa Alberto
Abstract excerpt
BACKGROUND: Intracardiac myxomas are frequent benign tumors of the heart and typically localize in the left atri- um and interatrial septum. When myxomas generate at other sites, they are designated as atypical. Mutations in the PRKAR1A gene (a tumor suppressor gene that encodes a protein kinase A [PKA] regulatory 1-alpha subunit) have been identified in both syndromic and non-syndromic cardiac atypical myxomas....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.