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Assessment of the clinical application of detecting EGFR, KRAS, PIK3CA and BRAF mutations in patients with non-small cell lung cancer using next-generation sequencing.

Scandinavian journal of clinical and laboratory investigation - 1 Sept 2016

Xu Xinnan, Yang Yang, Li Hui, Chen Zhao, Jiang Gening, Fei Ke

Abstract excerpt

BACKGROUND: Next-generation sequencing (NGS) has been widely applied in clinical research, while its application in routine clinical molecular testing requires careful validation. The aim of our study was to assess the clinical usefulness of the NextDaySeq Lung panel on Ion Torrent™ PGM in mutation detection of actionable genes in lung cancer. METHODS: The NextDaySeq assay was evaluated by blinded comparisons to...

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Identifiers

PMID: 27215271
DOI: 10.1080/00365513.2016.1183813

Genes

BRAF
EGFR
KRAS
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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