Article
Regulation of viral gene expression by the herpes simplex virus 1UL24 protein (HSV-1UL24 inhibits accumulation of viral transcripts).
Virology - 1 Aug 2016
Sanabria-Solano Carolina, Gonzalez Carmen Elena, Richerioux Nicolas, Bertrand Luc, Dridi Slimane, Griffiths Anthony, Langelier Yves, Pearson Angela
Abstract excerpt
UL24 is conserved among all Herpesviridae. In herpes simplex virus 1 (HSV-1), UL24 mutations lead to reduced viral titers both in cell culture and in vivo, and reduced pathogenicity. The human cytomegalovirus ortholog of UL24 has a gene regulatory function; however, it is not known whether other UL24 orthologs also affect gene expression. We discovered that in co-transfection experiments, expression of UL24...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
