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Article

A Study of Single Nucleotide Polymorphisms of the SLC19A1/RFC1 Gene in Subjects with Autism Spectrum Disorder.

International journal of molecular sciences - 19 May 2016

Mahmuda Naila Al, Yokoyama Shigeru, Huang Jian-Jun, Liu Li, Munesue Toshio, Nakatani Hideo, Hayashi Kenshi, Yagi Kunimasa, Yamagishi Masakazu, Higashida Haruhiro

Abstract excerpt

Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with complex genetic etiology. Recent studies have indicated that children with ASD may have altered folate or methionine metabolism, suggesting that the folate-methionine cycle may play a key role in the etiology of ASD. SLC19A1, also referred to as reduced folate carrier 1 (RFC1), is a member of the solute carrier group of transporters...

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Source

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Identifiers

PMID: 27213354
DOI: 10.3390/ijms17050772
PMCID: PMC4881591

Genes

RFC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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