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Article

Association between MTHFR gene polymorphisms and the risk of autism spectrum disorders: a meta-analysis.

Autism research : official journal of the International Society for Autism Research - 1 Oct 2013

Pu Danhua, Shen Yiping, Wu Jie

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is essential for DNA biosynthesis and the epigenetic process of DNA methylation, and its gene polymorphisms have been implicated as risk factors for birth defects, neurological disorders, and cancers. However, reports on the association of MTHFR polymorphisms with autism spectrum disorders (ASD) are inconclusive. Therefore, we investigated the relationship of the MTHFR...

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Identifiers

PMID: 23653228
DOI: 10.1002/aur.1300

Genes

MTHFR

Variants

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