Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis.

BMC pediatrics - 24 Sept 2020

Li Yan, Qiu Shuang, Shi Jikang, Guo Yanbo, Li Zhijun, Cheng Yi, Liu Yawen

Abstract excerpt

BACKGROUND: Autism spectrum disorder (ASD) is becoming increasingly prevalent of late. Methylenetetrahydrofolate reductase (MTHFR) has a significant role in folate metabolism. Owing to the inconsistencies and inconclusiveness on the association between MTHFR single nucleotide polymorphism (SNP) and ASD susceptibilities, a meta-analysis was conducted to settle the inconsistencies. METHODS: For this meta-analysis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Autism Spectrum Disorder
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 32972375
DOI: 10.1186/s12887-020-02330-3
PMCID: PMC7517654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis.PMID 32972375Read ↗

Association between MTHFR gene polymorphisms and the risk of autism spectrum disorders: a meta-analysis.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism with autism: evidence of genetic susceptibility.Semantic proximity Read ↗

Genetics of autism spectrum disorder: an umbrella review of systematic reviews and meta-analyses.Semantic proximity Read ↗

Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders.Semantic proximity Read ↗

Analysis of association between components of the folate metabolic pathway and autism spectrum disorder in eastern Indian subjects.Semantic proximity Read ↗

Comprehensive systematic review and meta-analysis of the association between common genetic variants and autism spectrum disorder.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase A1298C genetic variant& risk of schizophrenia: A meta-analysis.Semantic proximity Read ↗

Association Study of Polymorphisms in Genes Relevant to Vitamin B12 and Folate Metabolism with Childhood Autism Spectrum Disorder in a Han Chinese Population.Semantic proximity Read ↗

Genetic Susceptibility to Autism Spectrum Disorders: Folate Pathway Polymorphisms, Mediterranean Diet and Evolutionary Insights.Semantic proximity Read ↗

Study of the C677T and 1298AC polymorphic genotypes of MTHFR Gene in autism spectrum disorderSemantic proximity Read ↗

Aberrations in folate metabolic pathway and altered susceptibility to autism.Semantic proximity Read ↗

MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications—A ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.