Article
Changes in posterior scleral collagen microstructure in canine eyes with an ADAMTS10 mutation.
Molecular vision - 1 Jan 2016
Boote Craig, Palko Joel R, Sorensen Thomas, Mohammadvali Ashkan, Elsheikh Ahmed, Komáromy András M, Pan Xueliang, Liu Jun
Abstract excerpt
PURPOSE: We aimed to characterize alterations in the posterior scleral collagen microstructure before detectable disease onset in a canine model of open-angle glaucoma caused by an ADAMTS10 mutation. METHODS: Collagen orientation, anisotropy degree (proportion of preferentially aligned collagen), and relative density were measured at 0.4 mm spatial resolution using synchrotron wide-angle X-ray scattering. For...
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