Article
Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Nov 2016
Yamasaki Seiji, Fujioka Takuma, Hayashi Katsuhiko, Yamasaki Suguru, Hayashi-Nishino Mitsuko, Nishino Kunihiko
Abstract excerpt
A large number of drug efflux transporters have been identified in Salmonella enterica serovar Typhimurium, and increased expression of these transporters confers drug resistance in this organism. Here we compared the respiration activities of the wild-type strain and a mutant with nine deleted transporters by phenotype microarray analysis. The mutant was susceptible to 66 structurally unrelated compounds...
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