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Article

Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials.

Antimicrobial agents and chemotherapy - 1 Feb 2007

Chen Sheng, Cui Shenghui, McDermott Patrick F, Zhao Shaohua, White David G, Paulsen Ian, Meng Jianghong

Abstract excerpt

The mechanisms involved in fluoroquinolone resistance in Salmonella enterica include target alterations and overexpression of efflux pumps. The present study evaluated the role of known and putative multidrug resistance efflux pumps and mutations in topoisomerase genes among laboratory-selected and naturally occurring fluoroquinolone-resistant Salmonella enterica serovar Typhimurium strains. Strains with...

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Source

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Identifiers

PMID: 17043131
DOI: 10.1128/AAC.00600-06
PMCID: PMC1797773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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