Article
Contribution of enhanced efflux to reduced susceptibility of Salmonella enterica serovar Choleraesuis to fluoroquinolone and other antimicrobials.
The Journal of veterinary medical science - 1 Feb 2011
Usui Masaru, Uchiyama Mariko, Baba Kotaro, Nagai Hidetaka, Yamamoto Yoshimi, Asai Tetsuo
Abstract excerpt
We examined antimicrobial susceptibility and efflux systems in laboratory-derived mutants of Salmonella enterica serovar Choleraesuis selected by culture on fluoroquinolone-containing plates. The mutants exhibited decreased susceptibilities to quinolones and several other antimicrobials. Mutations in the gyrA gene were not always found in the mutants. Accumulation assays revealed that intracellular enrofloxacin...
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