SUGP1 is a novel regulator of cholesterol metabolism.

doi:10.1093/hmg/ddw151

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Article

SUGP1 is a novel regulator of cholesterol metabolism.

Human molecular genetics - 15 Jul 2016

Kim Mee J, Yu Chi-Yi, Theusch Elizabeth, Naidoo Devesh, Stevens Kristen, Kuang Yu-Lin, Schuetz Erin, Chaudhry Amarjit S, Medina Marisa W

Abstract excerpt

A large haplotype on chromosome 19p13.11 tagged by rs10401969 in intron 8 of SURP and G patch domain containing 1 (SUGP1) is associated with coronary artery disease (CAD), plasma LDL cholesterol levels, and other energy metabolism phenotypes. Recent studies have suggested that TM6SF2 is the causal gene within the locus, but we postulated that this locus could harbor additional CAD risk genes, including the...

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Identifiers

PMID: 27206982
DOI: 10.1093/hmg/ddw151
PMCID: PMC5181593

Genes

SUGP1
CAD
HMGCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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