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Comparison of intramedullary myeloma and corresponding extramedullary soft tissue plasmacytomas using genetic mutational panel analyses

20 May 2016

Abstract excerpt

Multiple Myeloma (MM) is characterized by growth and proliferation of clonal plasma cells in the bone marrow (BM), and these plasma cells depend heavily on this BM microenvironment. In a subset of patients, the myeloma cells can spread hematogenously to soft tissues and these extramedullary myeloma (EM) lesions may be found in up to 30% of MM patients, the majority occurring during the course of the disease. 1...

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PMID: 27206246
DOI: 10.1038/bcj.2016.35

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