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Article

Integration of clinical outcomes and molecular features in extramedullary disease in multiple myeloma.

Blood cancer journal - 23 Dec 2024

Nakamoto-Matsubara Rie, Nardi Valentina, Horick Nora, Fukushima Tsuyoshi, Han Ryan S, Shome Rajib, Ochi Kiyosumi, Panaroni Cristina, Fulzele Keertik, Rexha Farah, Branagan Andrew R, Cirstea Diana, Yee Andrew J, Scadden David T, Raje Noopur S

Abstract excerpt

Multiple myeloma (MM) remains incurable despite novel therapeutics. A major contributor to the development of relapsed/refractory and resistant MM is extraosseous extramedullary disease (EMD), whose molecular biology is still not fully understood. We analyzed 528 MM patients who presented to our institution between 2014 and 2021 and who had undergone molecular testing. We defined EMD as organ plasmacytoma...

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Identifiers

PMID: 39715752
DOI: 10.1038/s41408-024-01190-9
PMCID: PMC11666541

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