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Article

A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests

8 Aug 2011

Abstract excerpt

BACKGROUND: Allergic contact dermatitis is an inflammatory skin disease that affects a significant proportion of the population. This disease is caused by an adverse immune response towards chemical haptens, and leads to a substantial economic burden for society. Current test of sensitizing chemicals rely on animal experimentation. New legislations on the registration and use of chemicals within pharmaceutical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 21824406
DOI: 10.1186/1471-2164-12-399

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