Article

Immune gene expression profiling reveals heterogeneity in luminal breast tumors

2019-01-09

Abstract excerpt

Disease heterogeneity of immune gene expression patterns of luminal breast cancer (BC) has not been well studied. We performed immune gene expression profiling of tumor and adjacent normal tissue in 92 Asian luminal BC patients and identified three distinct immune subtypes. Tumors in one subtype exhibited signs of T-cell activation, lower ESR1/ESR2 expression ratio and higher expression of immune checkpoint genes...

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Literature Corpus work: f8916d12-2abe-50b1-93f7-a86da051a143
DOI: 10.1101/515486

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