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Article

Early Stress History Alters Serum Insulin‐Like Growth Factor‐1 and Impairs Muscle Mitochondrial Function in Adult Male Rats

19 May 2016

Abstract excerpt

Early-life adversity is associated with an enhanced risk for adult psychopathology. Psychiatric disorders such as depression exhibit comorbidity for metabolic dysfunction, including obesity and diabetes. However, it is poorly understood whether, besides altering anxiety and depression-like behaviour, early stress also evokes dysregulation of metabolic pathways and enhances vulnerability for metabolic disorders....

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PMID: 27196416
DOI: 10.1111/jne.12397

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