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Article

Cardiorenal metabolic biomarkers link early life stress to risk of non-communicable diseases and adverse mental health outcomes.

Scientific reports - 6 Aug 2020

Poplawski Janet, Radmilovic Ana, Montina Tony D, Metz Gerlinde A S

Abstract excerpt

Stress is one of the most critical determinants of lifetime health and increases the risk of chronic non-communicable diseases. To gain insight into underlying environment-gene interactions, we analyzed the cardiorenal metabolome of adult mice exposed to multidimensional early-life transportation stress. Using proton nuclear magnetic resonance (1H NMR) spectroscopy, we show that early life stress permanently...

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Identifiers

PMID: 32764629
DOI: 10.1038/s41598-020-69866-3
PMCID: PMC7413400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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