Article
The ACTN3 R577X polymorphism affects the lipid profile and the prognosis of nutritional intervention in HIV-positive patients.
Nutrition research (New York, N.Y.) - 1 Jun 2016
Aranalde Laura C R, Pederzoli Bruna S, Marten Thais, Barros Flavio C, Basso Rossana P, Silveira Jussara M, Valle Sandra C, Pieniz Simone, Araujo Ronaldo C, Paredes-Gamero Edgar J, Schadock Ines, Schneider Augusto, Barros Carlos C
Abstract excerpt
The hypothesis of the present study is that the polymorphisms in the APOC3, CEPT, ACE, and ACTN3 genes can affect the outcome of nutritional intervention and the plasma lipid profile of HIV+ patients. To test the hypothesis, genetic material was collected from buccal cells, and serum was collected for biochemical analysis. Sixty-five patients were analyzed. The incorporation of protease inhibitor (PI) was more...
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