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Article

PD-L1 polymorphism can predict clinical outcomes of non-small cell lung cancer patients treated with first-line paclitaxel-cisplatin chemotherapy.

Scientific reports - 16 May 2016

Lee Shin Yup, Jung Deuk Kju, Choi Jin Eun, Jin Cheng Cheng, Hong Mi Jeong, Do Sook Kyung, Kang Hyo-Gyoung, Lee Won Kee, Seok Yangki, Lee Eung Bae, Jeong Ji Yun, Shin Kyung Min, Yoo Seung Soo, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Park Jae Yong

Abstract excerpt

This study was conducted to investigate whether polymorphisms of genes involved in immune checkpoints can predict the clinical outcomes of patients with advanced stage non-small cell lung cancer (NSCLC) after 1st line paclitaxel-cisplatin chemotherapy. A total of 379 NSCLC patients were enrolled. Twelve single nucleotide polymorphisms (SNPs) of PD-1, PD-L1, and CTLA-4 genes were selected and genotyped. The...

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Identifiers

PMID: 27181838
DOI: 10.1038/srep25952
PMCID: PMC4867646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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