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Article

PD-L1 SNPs as biomarkers to define benefit in patients with advanced NSCLC treated with immune checkpoint inhibitors.

Tumori - 1 Feb 2022

Minari Roberta, Bonatti Francesco, Mazzaschi Giulia, Dodi Alessandra, Facchinetti Francesco, Gelsomino Francesco, Cinquegrani Gloria, Squadrilli Anna, Bordi Paola, Buti Sebastiano, Bersanelli Melissa, Leonetti Alessandro, Cosenza Agnese, Ferri Leonarda, Rapacchi Elena, Quaini Federico, Ardizzoni Andrea, Tiseo Marcello

Abstract excerpt

OBJECTIVE: To investigate the role of CTLA-4, PD-1 (programmed death-1), and PD-L1 (programmed death-ligand 1) single nucleotide polymorphisms (SNPs) in predicting clinical outcome of patients with advanced non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs). METHODS: A total of 166 consecutive patients were included. We correlated SNPs with clinical benefit, progression-free...

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PMID: 34002648
DOI: 10.1177/03008916211014954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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