Article
Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping.
Nature communications - 16 May 2016
Augustsson Per, Karlsen Jonas T, Su Hao-Wei, Bruus Henrik, Voldman Joel
Abstract excerpt
Mechanical phenotyping of single cells is an emerging tool for cell classification, enabling assessment of effective parameters relating to cells' interior molecular content and structure. Here, we present iso-acoustic focusing, an equilibrium method to analyze the effective acoustic impedance of single cells in continuous flow. While flowing through a microchannel, cells migrate sideways, influenced by an...
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