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Article

Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation.

American heart journal - 1 May 2016

Roberts Jason D, Dewland Thomas A, Glidden David V, Hoffmann Thomas J, Arking Dan E, Chen Lin Y, Psaty Bruce M, Olgin Jeffrey E, Alonso Alvaro, Heckbert Susan R, Marcus Gregory M

Abstract excerpt

BACKGROUND: Renin-angiotensin system (RAS) inhibition via angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers may reduce the risk of developing atrial fibrillation (AF) in certain populations, but the evidence is conflicting. Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with AF, potentially identifying clinically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27179719
DOI: 10.1016/j.ahj.2016.02.002
PMCID: PMC4873713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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