Article
Lack of replication in polymorphisms reported to be associated with atrial fibrillation.
Heart rhythm - 1 Mar 2011
Sinner Moritz F, Lubitz Steven A, Pfeufer Arne, Makino Seiko, Beckmann Britt-Maria, Lunetta Kathryn L, Steinbeck Gerhard, Perz Siegfried, Rahman Rosanna, Sonni Akshata, Greenberg Steven M, Furie Karen L, Wichmann H-Erich, Meitinger Thomas, Peters Annette, Benjamin Emelia J, Rosand Jonathan, Ellinor Patrick T, Kääb Stefan
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is the most common sustained arrhythmia and has a substantial heritable component. Numerous associations between single nucleotide polymorphisms (SNPs) and AF have been described, but few have been replicated. OBJECTIVE: We sought to systematically replicate SNPs that are reported to be associated with AF in two large study samples of European descent. METHODS: We searched...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.