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Article

Quorum-sensing inhibition abrogates the deleterious impact of Pseudomonas aeruginosa on airway epithelial repair.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2016

Ruffin Manon, Bilodeau Claudia, Maillé Émilie, LaFayette Shantelle L, McKay Geoffrey A, Trinh Nguyen Thu Ngan, Beaudoin Trevor, Desrosiers Martin-Yvon, Rousseau Simon, Nguyen Dao, Brochiero Emmanuelle

Abstract excerpt

Chronic Pseudomonas aeruginosa lung infections are associated with progressive epithelial damage and lung function decline. In addition to its role in tissue injury, the persistent presence of P. aeruginosa-secreted products may also affect epithelial repair ability, raising the need for new antivirulence therapies. The purpose of our study was to better understand the outcomes of P. aeruginosa exoproducts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27178322
DOI: 10.1096/fj.201500166R
PMCID: PMC6191002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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