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Article

Natural Selection in Virulence Genes of Francisella tularensis.

Journal of molecular evolution - 1 Jun 2016

Gunnell Mark K, Robison Richard A, Adams Byron J

Abstract excerpt

A fundamental tenet of evolution is that alleles that are under negative selection are often deleterious and confer no evolutionary advantage. Negatively selected alleles are removed from the gene pool and are eventually extinguished from the population. Conversely, alleles under positive selection do confer an evolutionary advantage and lead to an increase in the overall fitness of the organism. These alleles...

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PMID: 27177502
DOI: 10.1007/s00239-016-9743-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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