Article
Association of IL12A Expression Quantitative Trait Loci (eQTL) With Primary Biliary Cirrhosis in a Chinese Han Population.
Medicine - 1 May 2016
Li Ping, Lu Guanting, Cui Ying, Wu Ziyan, Chen Si, Li Jing, Wen Xiaoting, Zhang Haoze, Mu Shijie, Zhang Fengchun, Li Yongzhe
Abstract excerpt
Genome-wide association studies in European individuals have revealed that IL12A is strongly associated with primary biliary cirrhosis (PBC). However, this association was not detected in replicative studies conducted in Chinese Han and Japanese populations.To verify contributions of genetic variants of IL12A to the pathogenesis of PBC in Chinese populations, a replicative study of 22 single nucleotide...
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