Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replicated association of 17q12-21 with susceptibility of primary biliary cirrhosis in a Japanese cohort.

Tissue antigens - 1 Jul 2011

Tanaka A, Invernizzi P, Ohira H, Kikuchi K, Nezu S, Kosoy R, Seldin M F, Gershwin M E, Takikawa H

Abstract excerpt

To examine the genetics of susceptibility to primary biliary cirrhosis (PBC), genome-wide association studies GWAS have been performed in patients of European ancestry and have shown the significant associations of IL12-related pathways, SPIB, IRF5-TNPO3, and 17q12-21. We tested whether these findings could be extended to a Japanese cohort, 303 Japanese PBC and 298 controls. We failed to detect significant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to beta Karyopherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 17

Share to Cohort Studies

Share to Genome-Wide Association Study

Share to Interferon Regulatory Factors

Share to Liver Cirrhosis, Biliary

Share to Receptors, Interleukin-12

Source

Identifiers

PMID: 21506939
DOI: 10.1111/j.1399-0039.2011.01684.x

Genes

SPIB
TNPO3
GSDMB
IKZF3
ZPBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replicated association of 17q12-21 with susceptibility of primary biliary cirrhosis in a Japanese cohort.PMID 21506939Read ↗

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.Semantic proximity Read ↗

Multiple genetic variants associated with primary biliary cirrhosis in a Han Chinese population.Semantic proximity Read ↗

Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis.Semantic proximity Read ↗

A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.Semantic proximity Read ↗

[Analysis of disease-pathway by identifying susceptible genes to primary biliary cirrhosis].Semantic proximity Read ↗

Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.Semantic proximity Read ↗

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.Semantic proximity Read ↗

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathwaysSemantic proximity Read ↗

Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants.Semantic proximity Read ↗

Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.Semantic proximity Read ↗

Progress in the genetics of primary biliary cirrhosis.Semantic proximity Read ↗

Genome-wide haplotype association analysis of primary biliary cholangitis risk in Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.