Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Analysis of SNPs in the ERCC5 Promoter in Advanced Colorectal Cancer Patients Treated With Oxaliplatin-Based Chemotherapy.

Medicine - 1 May 2016

Chen Jianfang, Luo Xi, Xie Ganfeng, Chen Keli, Jiang Heng, Pan Feng, Li Jianjun, Ruan Zhihua, Pang Xueli, Liang Houjie

Abstract excerpt

The promoter is the center for regulation of gene transcription due to containing numerous transcription factor binding sites. The aim of the study was to determine whether genetic variations at excision repair cross complementation group 5 (ERCC5) promoter could affect transcription factor binding and whether such single nucleotide polymorphism (SNP)-dependent binding could affect gene expression, drug response,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Electrophoretic Mobility Shift Assay

Share to Endonucleases

Share to Organoplatinum Compounds

Share to Oxaliplatin

Share to Pharmacogenetics

Source

Open in PubMed Open full text

Identifiers

PMID: 27175691
DOI: 10.1097/MD.0000000000003652
PMCID: PMC4902533

Genes

ERCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Analysis of SNPs in the ERCC5 Promoter in Advanced Colorectal Cancer Patients Treated With Oxaliplatin-Based Chemotherapy.PMID 27175691Read ↗

ERCC5 promoter polymorphisms at -763 and +25 predict the response to oxaliplatin-based chemotherapy in patients with advanced colorectal cancer.Semantic proximity Read ↗

Association between polymorphism in the promoter region of lncRNA GAS5 and the risk of colorectal cancerSemantic proximity Read ↗

Genetic variants as potential predictive biomarkers in advanced colorectal cancer patients treated with oxaliplatin‐based chemotherapySemantic proximity Read ↗

Association analysis of ERCC5 gene polymorphisms with risk of breast cancer in Han women of northwest China.Semantic proximity Read ↗

Association between ERCC5 gene rs17655 polymorphism and the risk of breast cancer: an updated meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms in ERCC1 and ERCC2 genes are associated with response to chemotherapy in osteosarcoma patients among Chinese population: a meta-analysis.Semantic proximity Read ↗

Genome-wide identification of chemosensitive single nucleotide polymorphism markers in colorectal cancers.Semantic proximity Read ↗

ERCC1 and XPD/ERCC2 polymorphisms' predictive value of oxaliplatin-based chemotherapies in advanced colorectal cancer has an ethnic discrepancy: a meta-analysis.Semantic proximity Read ↗

Role of ERCC5 promoter polymorphisms in response to platinum-based chemotherapy in patients with advanced non-small-cell lung cancer.Semantic proximity Read ↗

Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1.Semantic proximity Read ↗

GSTP1, ERCC1 and ERCC2 polymorphisms, expression and clinical outcome of oxaliplatin-based adjuvant chemotherapy in colorectal cancer in Chinese population.Semantic proximity Read ↗

Relationship between DNA repair gene XPD751 single-nucleotide polymorphisms and prognosis of colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.