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Article

ERCC5 promoter polymorphisms at -763 and +25 predict the response to oxaliplatin-based chemotherapy in patients with advanced colorectal cancer.

Cancer biology & therapy - 1 Jul 2009

Chen Jianfang, Xie Fangwei, Chen Keli, Wang Dong, Jiang Heng, Li Jianjun, Pan Feng, Chen Shixu, Zhang Yanling, Ruan Zhihua, Huang Haihui, Zou Lan, Liang Houjie

Abstract excerpt

This study aimed to investigate whether single nucleotide polymorphisms (SNPs) in the promoter of the excision repair cross complementation group 5 (ERCC5) gene influences response to oxaliplatin-based chemotherapy. Eighty-three patients with cytologically or histologically confirmed advanced colorectal cancer (CRC), at least one measurable lesion and underwent oxaliplatin-based chemotherapy were studied. To this...

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Identifiers

PMID: 19458483
DOI: 10.4161/cbt.8.14.8889

Genes

ERCC5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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ERCC5 promoter polymorphisms at -763 and +25 predict the response to oxaliplatin-based chemotherapy in patients with advanced colorectal cancer.PMID 19458483Read ↗

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