Article
Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.
Medicine - 1 May 2016
Xu Kuanfeng, Jiang Lin, Zhang Mei, Zheng Xuqin, Gu Yong, Wang Zhixiao, Cai Yun, Dai Hao, Shi Yun, Zheng Shuai, Chen Yang, Ji Li, Xu Xinyu, Chen Heng, Sun Min, Yang Tao
Abstract excerpt
Recently, rs163182 in KCNQ1, rs7612463 in UBE2E2, rs7119 in HMG20A, and rs6815464 in MAEA were discovered as type 2 diabetes (T2D) loci unique to Asians, and rs13342692 in SLC16A11 were newly reported as T2D loci in multiethnicities by genome-wide association (GWA) studies. The aim of the present study is to ascertain the potential associations between these variants and T2D risk in the Chinese population, and...