Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han population.

doi:10.18388/abp.2014_936

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Article

Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han population.

Acta biochimica Polonica - 1 Jan 2015

Kazakova Elena V, Wu Yanhui, Zhou Zhongyu, Chen Meijun, Wang Tongtong, Tong Huixin, Zhuang Tianwei, Sun Lulu, Qiao Hong

Abstract excerpt

UBE2E2 encodes ubiquitin-conjugating enzyme E2E2, which plays an important role in the synthesis and secretion of insulin. Two previous studies indicated that SNPs in UBE2E2 were associated with risk for type 2 diabetes mellitus (T2DM) in the Japanese and Korean populations, respectively. We examined the association of one SNP in this gene, rs7612463, with the risk of T2DM in 1957 Han participants in northeastern...

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PMID: 26020062
DOI: 10.18388/abp.2014_936

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