Article
Hepatic autophagy contributes to the metabolic response to dietary protein restriction.
Metabolism: clinical and experimental - 1 Jun 2016
Henagan Tara M, Laeger Thomas, Navard Alexandra M, Albarado Diana, Noland Robert C, Stadler Krisztian, Elks Carrie M, Burk David, Morrison Christopher D
Abstract excerpt
Autophagy is an essential cellular response which acts to release stored cellular substrates during nutrient restriction, and particularly plays a key role in the cellular response to amino acid restriction. However, there has been limited work testing whether the induction of autophagy is required for adaptive metabolic responses to dietary protein restriction in the whole animal. Here, we found that moderate...
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