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Article

Role of Autophagy in the Control of Body Metabolism

1 Jan 2013

Abstract excerpt

Autophagy plays a crucial role in the maintenance of cellular nutrient balance and the function of organelles such as mitochondria or the endoplasmic reticulum, which are important in intracellular metabolism, insulin release, and insulin sensitivity. In the insulin-producing pancreatic β-cells, autophagy is important in the maintenance of β-cell mass, structure, and function. Mice with deficiencies in...

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PMID: 24396643
DOI: 10.3803/enm.2013.28.1.6

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