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Genetic Variability in Probe Binding Regions Explains False Negative Results of a Molecular Assay for the Detection of Dengue Virus.

Vector borne and zoonotic diseases (Larchmont, N.Y.) - 1 Jul 2016

Koo Carmen, Kaur Simrandeep, Teh Zhi-Yong, Xu Helen, Nasir Amna, Lai Yee-Ling, Khan Erum, Ng Lee-Ching, Hapuarachchi Hapuarachchige C

Abstract excerpt

Dengue fever is currently the most prevalent disease caused by mosquito-borne flaviviruses. Despite being potentially fatal, there are no specific antiviral therapies for Dengue virus (DENV) infections. Therefore, early, accurate, and rapid diagnosis plays an important role in proper patient management. In this study, we evaluated the performance of a probe-based real-time RT-PCR (rRT-PCR) assay against that of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27172387
DOI: 10.1089/vbz.2015.1899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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