Article
Structure and function of the parvoviral NS1 protein: a review.
Virus genes - 1 Apr 2023
Xie Qianqian, Wang Jigui, Gu Chenchen, Wu Jing, Liu Weiquan
Abstract excerpt
Parvoviruses possess a single-stranded DNA genome of about 5 kb, which contains two open reading frames (ORFs), one encoding nonstructural (NS) proteins, the other capsid proteins. The NS1 protein contains an N-terminal origin-binding domain, a helicase domain, and a C-terminal transactive domain, and is essential for effective viral replication and production of infectious virus. We first summarize the...
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