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Article

MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus

12 May 2016

Abstract excerpt

UNLABELLED: Multiple cellular pathways are regulated by small ubiquitin-like modifier (SUMO) modification, including ubiquitin-mediated proteolysis, signal transduction, innate immunity, and antiviral defense. In the study described in this report, we investigated the effects of SUMO on the replication of two members of the Rhabdoviridae family, vesicular stomatitis virus (VSV) and rabies virus (RABV). We show...

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PMID: 27170750
DOI: 10.1128/jvi.00722-16

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