Article
Predicting genotype compositions in norovirus seasons in Japan.
Microbiology and immunology - 1 Jun 2016
Suzuki Yoshiyuki, Doan Yen Hai, Kimura Hirokazu, Shinomiya Hiroto, Shirabe Komei, Katayama Kazuhiko
Abstract excerpt
Noroviruses cause acute gastroenteritis. Since multiple genotypes of norovirus co-circulate in humans, changing the genotype composition and eluding host immunity, development of a polyvalent vaccine against norovirus in which the genotypes of vaccine strains match the major strains in circulation in the target season is desirable. However, this would require prediction of changes in the genotype composition of...
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