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Predicting antigenic variants of H1N1 influenza virus based on epidemics and pandemics using a stacking model

21 Dec 2018

Abstract excerpt

H1N1 is the earliest emerging subtype of influenza A viruses with available genomic sequences, has caused several pandemics and seasonal epidemics, resulting in millions of deaths and enormous economic losses. Timely determination of new antigenic variants is crucial for the vaccine selection and flu prevention. In this study, we chronologically divided the H1N1 strains into several periods in terms of the...

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PMID: 30576319
DOI: 10.1371/journal.pone.0207777

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