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Article

The transmission dynamics of Norovirus in England: A genotype-specific modelling study.

Epidemics - 1 Dec 2025

Vesga Juan F, Douglas Amy, Celma Cristina, Knock Edward S, Baguelin Marc, Edmunds W John

Abstract excerpt

BACKGROUND: Norovirus is the leading cause of acute gastroenteritis cases in England and worldwide, with diverse co-circulating genotypes. Vaccine candidates targeting multiple genotypes are advancing. However, most transmission models still focus on single-strain dynamics, limiting their ability to assess the role of co-circulating strains on population burden. METHODS: We developed an age structured multistrain...

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PMID: 41319617
DOI: 10.1016/j.epidem.2025.100875

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