Article
The thrombin generation assay distinguishes inhibitor from non-inhibitor patients with severe haemophilia A.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2016
Mancuso M E, Chantarangkul V, Clerici M, Fasulo M R, Padovan L, Scalambrino E, Peyvandi F, Tripodi A, Santagostino E
Abstract excerpt
INTRODUCTION: Patients with haemophilia A (HA) have impaired thrombin generation (TG) capacity and TG assay (TGA) values are linearly related to plasma factor VIII (FVIII) levels. AIM: This study carried out in patients with unmeasurable FVIII (<1 IU dL(-1) ) was aimed at unravelling any difference in TG capacity in patients with or without inhibitors. METHODS: Blood samples were collected from patients in a...
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