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Article

IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis.

Annals of the rheumatic diseases - 1 Dec 2016

Gracey Eric, Qaiyum Zoya, Almaghlouth Ibrahim, Lawson Daeria, Karki Susan, Avvaru Naga, Zhang Zhenbo, Yao Yuchen, Ranganathan Vidya, Baglaenko Yuriy, Inman Robert D

Abstract excerpt

OBJECTIVE: Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown origin in which interleukin (IL) 17 has been genetically and therapeutically recognised as a key player. Identification of the cellular sources and inducers of IL-17 is crucial in our understanding of the drivers of inflammation in AS. Recently, mucosal-associated invariant T (MAIT) cells have been implicated in autoimmune...

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PMID: 27165176
DOI: 10.1136/annrheumdis-2015-208902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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